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Studies - Food Base Vitamin C |
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 In numerous studies carried out on Food Base Vitamin C research has concluded that the Food Base Vitamin C acts very differently to synthetic Vitamin C. The Food Base is more slowly absorbed, it has higher Bioavailability (35% more than synthetic ascorbate), more gets into the plasma (54.5% more than synthetic ascorbate), and more gets into the red blood cells (74.4% more than synthetic ascorbate), it is retained substantially longer, less was excreted in urine (56% less than synthetic ascorbate), and was still effective after 24 hours
One long term study, at the 74% confidence level, showed the Food Base Citrus extract Vitamin C to be 1210% (12 times) more bio available than Ascorbic Acid in the serum.
Studies carried out on Vitamin C are:
1. Vinson J.A.; Courey J.M. and Maro N.P., "Comparison of Two Forms of Vitamin Con Galactose Cataracts", Nutrition Research, 1992, 12~ 915-922.
'The combination of ascorbic acid and citrus extract are more effective than ascorbic acid alone as a supplement to increase lens ascorbate and slow down the progression of galactose cataracts.'
2. Vinson J.A. and Hsu C., "Effect of Vitamin A, E and a Citrus Extract on in vitro and in vivo Lipid Peroxidation", Medical Science Research, 1992, 20, 145-146.
Antioxidant supplements, especially in combination where additivity is possible should be investigated as therapy for lowering Lipid Peroxidation.'
3. Vinson J.A. Lupia J., Pettinato L.; Wang H-W. and Rudolph K., "In Vitro and In Vivo Reduction of Erythrocyte Sorb it'll by Ascorbic Acid", Diabetes, 1989, 38, 8, 1036-1041.
'Ascorbic Acid alone and Citrus fruit medium decreased erythrocyte sorbitol by 12.6 and 27.2% respectively with the latter being significantly more effective.'
4. Vinson J.A.; Bose P.; Lemoine L. and Hsaio K., 1989 in Southgate D.A.T.; Johnson I.T. and Fenwick G.R., (Eds.), Nutrient Availability: Chemical and Biological Aspects, 125-127, Royal Society of Chemistry, Thomas Graham House, Cambridge, U.K.
'Yeast trace elements and natural vitamins are more slowly absorbed in animals and man; are more bioavailable; and are therefore the preferred form for supplementation.'
5. Vinson J.A.; Bose P., "Comparative Bioavailability to humans of Ascorbic Acid Alone or in a Citrus Extract", American Journal of Clinical Nutrition, 1988, 48, 3, 601-604. 'Ascorbate in the Citrus extract was found to be more bioavailable than Ascorbic acid alone in human subjects.'
6. Vinson J.A.; Bose P., "Bioavailability of Synthetic Ascorbic Acid and a Citrus Extract", Annals of the New York Academy of Sciences, 3rd Conference on Vitamin C, 1987, 498, 525-526.
'Citrus Extract has been shown in guinea pigs and humans to be more absorbed than Ascorbic Acid and to remain in the body for a longer period of time. Citrus Extract is thus the preferred form of ascorbate for supplementation.'
7. Vinson J.A., "Comparison of Natural and Synthetic Vitamin C on the Formation of Sugar Cataracts", 1984, Unpublished Data.
'The natural Vitamin C was more effective than synthetic Vitamin C -In decreasing both the rate of cataract formation and the severity of such cataracts.'
8. Vinson J.A., "Comparative Bioavailability of Synthetic and Natural Vitamin C in Guinea Pigs", Nutrition Reports International, 1983, 27, 4, 875-880.
'The bio availability of the natural Vitamin C was significantly greater than that of the synthetic Ascorbic Acid.'
9. Vinson J.A., "Bioavailability of Vitamin C", 1991. Unpublished Data.
'Citrus extract was 1210% more bioavailable than USP Ascorbic Acid.'
10. Vinson J.A., "Citrus Extract and Human Lipids", 1988, Unpublished Data.
'Overall an 80% decline in risk in heart attacks occurred due to citrus extract supplementation.'
11. Cahill R.J.; O'Sullivan K.R.; Mathias P.M.; Beattie S.; Hamilton H. and O'Morain C., "Effects of vitamin antioxidant supplementation on cell kinetics of patients with adenomatous polyps", Gut, 1993, 34, 963-967.
'These findings indicate that prolonged supplementation with Vitamin C may reduce the recurrence of adenomatous polyps.'
12. Vinson J.A., "Human Supplementation with Different forms of Vitamin C", 1991, Unpublished Data.
'The Citrus Fruit Media produced a significantly greater rise in Red Blood Cell Ascorbate and Plasma Ascorbate levels than Ascorbic Acid alone.'
13. Vinson J.A., Lupia, 3., Pettinato, L., Wang, H.W. and Rudolph, K., "In vitro Red Blood Cell Inhibition of Sorbitol and Stimulation of Myomositol uptake by Ascorbic Acid alone or in a citrus extract", 1989, Diabetes, 38, 215A.
14. Baker, H. and Frank, 0., "Effects of Renatured Vitamin C on Human", 1983, Unpublished.
15. Vinson, JA. and Howard, III, T.B., "In vitro Inhibition of Protein Glycation and advanced Glycosylation End Product by Vitamins and Nutrients", Unpublished, 1992. |
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